How Drug That Sits On Acetylcholine Receptors Will Affect Muscle Function

Intoduction

According to Thomas (2008), Acetylcholine refers to a neurotransmitter that is located in the brain, and it helps in the transmission of electrical impulse that is produced within the central nervous system (CNS). There are two types of receptors Acetylcholine in the CNS namely, nicotinic and muscarinic. The molecules of Acetylcholine bind on the nicotinic and muscarinic receptors to generate a cholinergic or a parasympathetic response, and hence, it plays a vital role in wakefulness, regulation of sleep, and human memory. Acetylcholine receptors in the CNS are divided into two categories, for example, the automatic and the somatic nervous systems (Aschenbrenner & Venable, 2009). The Acetylcholine receptors play a significant role in the activation of the muscles cells. Besides, it enhances human attention and boosts sensory perception. In this regard, a drug that sits on the Acetylcholine receptors will inhibit the contraction and expansion, and hence, limits the function of the muscles as follows.

Anticholinergic is an example of drugs that sit on Acetylcholine receptors. Anticholinergic causes a blockage in the Acetylcholine receptors, and therefore, Acetylcholine will not bind on the nicotinic or muscarinic receptors within the lungs (Thomas, 2008). As a result, appropriate electric signals will not be generated in the CNS, and hence, the muscles of the lungs and bronchioles will not contract normally, and therefore, the airways will remain open allowing asthmatic patients to breathe.

Drugs used in the treatment of Myasthenia Gravis is also another type of drug that sits on the Acetylcholine receptors. These drugs can either destroy or block the Acetylcholine receptors that are located between the nerves and the muscles. The blockage will prevent Acetylcholine from binding on the muscle cells. As a result, there will no electric response within the CNS, and hence, no muscle contraction (Aschenbrenner & Venable, 2009).